Abstract:

Isoprenoids, including sterols, dolichols, ubiquinones, chlorophylls, carotenoids, and growth regulators etc., are essential for organism growth and development. They are synthesized by a series of enzymes involved in mevalonate pathway. This paper summarized the progress in biological characteristics, gene cloning, and gene expression of rate-limited enzyme, which would provide theoretical basis for application of mevalonate kinase gene in controlling disease and pest, and improving animal and crop.

Key words: isoprenoid, mevalonate kinase, genes, biological characteristics

摘要：

类异戊二烯是维持生物生长发育等所必需的重要有机物质,包括甾醇、长萜醇、辅酶Q、叶绿素和生长调节剂等多种重要物质,是通过甲羟戊酸代谢途径的一系列酶酶促反应合成的。综述了该途径中的限速酶之一甲羟戊酸激酶的生物学特性、基因克隆及表达等方面的研究进展,旨在为其病虫害控制、动植物改良中的应用提供依据。

关键词: 类异戊二烯;甲羟戊酸激酶;基因;生物学特性