Journal of Agricultural Science and Technology ›› 2022, Vol. 24 ›› Issue (12): 160-166.DOI: 10.13304/j.nykjdb.2022.1090
• SAFETY SUPERVISION • Previous Articles
Xujing WANG1(), Yongliang YAN1, Youhua WANG1, Qiaoling TANG1, Yue JIAO2(
), Zhixing WANG1(
)
Received:
2022-12-13
Accepted:
2022-12-16
Online:
2022-12-15
Published:
2023-02-06
Contact:
Yue JIAO,Zhixing WANG
王旭静1(), 燕永亮1, 王友华1, 唐巧玲1, 焦悦2(
), 王志兴1(
)
通讯作者:
焦悦,王志兴
作者简介:
王旭静 E-mail:wangxujing@caas.cn
基金资助:
CLC Number:
Xujing WANG, Yongliang YAN, Youhua WANG, Qiaoling TANG, Yue JIAO, Zhixing WANG. Progress on Agricultural Synthetic Biology Development and Risk Management[J]. Journal of Agricultural Science and Technology, 2022, 24(12): 160-166.
王旭静, 燕永亮, 王友华, 唐巧玲, 焦悦, 王志兴. 农业合成生物研发与风险管理[J]. 中国农业科技导报, 2022, 24(12): 160-166.
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URL: https://nkdb.magtechjournal.com/EN/10.13304/j.nykjdb.2022.1090
1 | MENG F K, ELLIS T. The second decade of synthetic biology: 2010—2020 [J/OL]. Nat. Commun., 2020,11(1): 5174 [2022-11-13]. . |
2 | 赵国屏. 合成生物学: 开启生命科学“会聚”研究新时代[J]. 中国科学院院刊, 2018, 33(11): 1135-1149. |
ZHAO G P. Synthetic biology: unsealing the convergence era of life science research [J]. Bull. Chin. Acad. Sci., 2018, 33(11): 1135-1149. | |
3 | 赵国屏. 合成生物学:从“造物致用”到产业转化[J].生物工程学报, 2022, 38(11):4001-4011. |
ZHAO G P. Synthetic biology: from “build-for-use” to commercialization [J]. Chin. J. Biotech., 2022, 38(11): 4001-4011. | |
4 | 林敏, 姚斌. 加强合成生物技术创新, 引领现代农业跨越发展[J].生物技术进展,2022,12(3):321-324. |
LIN M, YAO B. Strengthening innovation in synthetic biotechnology and leading the leapfrog development of modern agriculture [J]. Curr. Biotech., 2022, 12(3): 321-324. | |
5 | HOBOM B. Gene surgery: on the threshold of synthetic biology [J]. Med. Klin., 1980,75(24): 834-841. |
6 | 刘海龙. 人工合成生命:有机生命的机械制造[J].山东科技大学学报(社会科学版), 2022, 24(4):1-11 |
LIU H L. Synthesizing life: the mechanical manufacture of organic life [J]. J. Shandong. Univ. Sci. Technol. (Soc. Sci.), 2022, 24(4): 1-11. | |
7 | MCADAMS H H, ARKIN A. Towards a circuit engineering discipline [J]. Curr. Biol., 2000, 10(8):318-320. |
8 | DIPINTE G, GAURI S, POOJA S, et al.. Synthetic biology in plants, a boon for coming decades [J]. Mol. Biotech., 2021, 63(12):1138-1154. |
9 | MARTIN V J, PITERA D J, WITHERS S T, et al.. Engineering a mevalonate pathway in escherichia coli for production of terpenoids [J]. Nat. Biotech., 2003, 21(7):796-802. |
10 | RO D K, PARADISE E M, OUELLET M, et al.. Production of the antimalarial drug precursor artemisinic acid in engineered yeast [J]. Nature, 2006, 440(7086):940-943. |
11 | GIBSON D G, GLASS J I, LARTIGUE C, et al.. Creation of a bacterial cell controlled by a chemically synthesized genome [J]. Science, 2010, 329(5987):52-56. |
12 | PADDON C J, WESTFALL P J, PITERA D J, et al.. High-level semi-synthetic production of the potent antimalarial artemisinin [J]. Nature, 2013, 496(7446):528-532. |
13 | CHEN G Q. Synthetic biology in China, UK and US [J]. Synth. Syst. Biotech., 2016, 1(4): 215. |
14 | 周光明, 陈大明, 熊燕, 等. 英国合成生物学规划及其影响与启示[J].中国细胞生物学学报, 2019, 41(11): 2091-2100. |
ZHOU G M, CHEN D M, XIONG Y, et al.. UK synthetic biology strategic planning and its enlightenment [J]. Chin. J. Cell. Biol., 2019, 41(11): 2091-2100. | |
15 | SHENDURE J, BALASUBRAMANIAN S, CHURCH G M, et al.. DNA sequencing at 40: past, present and future [J]. Nature, 2017, 550(7676): 345-353. |
16 | YU W, YAU Y, BIRCHLER J A. Plant artificial chromosome technology and its potential application in genetic engineering [J]. Plant Biotech. J., 2016, 14(5):1175-1182. |
17 | PALLUK S, ARLOW D H, DE ROND T, et al.. De novo DNA synthesis using polymerase-nucleotide conjugates [J]. Nat. Biotech., 2018, 36(7): 645-650. |
18 | VENTER J C, GLASS J I, HUTCHISON C A, et al.. Synthetic chromosomes, genomes, viruses, and cells [J]. Cell, 2022, 185(15): 2708-2724. |
19 | SCHMID B, ZELLER S. Faculty opinions recommendation of creation of a bacterial cell controlled by a chemically synthesized genome [J]. Science, 2010, 329(5987): 52-56. |
20 | JONES A M, DANIELSON J Å, MANOJKUMAR S N, et al.. Abscisic acid dynamics in roots detected with genetically encoded FRET sensors [J/OL]. Elife, 2014, 3: e01741 [2022-11-13]. . |
21 | MUKHERJEE P, BANERJEE S, WHEELER A, et al.. Live imaging of inorganic phosphate in plants with cellular and subcellular resolution [J]. Plant. Physiol., 2015, 167(3): 628-638. |
22 | WONG M H, GIRALDO J P, KWAK S, et al.. Nitroaromatic detection and infrared communication from wild-type plants using plant nanobionics [J]. Nat. Materials, 2017, 16(2): 264-272. |
23 | BLANCQUAERT D, VAN DAELE J, STROBBE S, et al.. Improving folate (vitamin B9) stability in biofortified rice through metabolic engineering [J]. Nat. Biotech., 2015, 33(10): 1076-1078. |
24 | SHEN B R, WANG L M, LIN X L, et al.. Engineering a new chloroplastic photorespiratory bypass to increase photosynthetic efficiency and productivity in rice [J]. Mol. Plant, 2019, 2 (12): 199-214. |
25 | MIETTINEN K, DONG L, NAVROT N, et al.. The seco-iridoid pathway from catharanthus roseus [J/OL]. Nat. Commun., 2014, 5(1):3606 [2022-11-13]. . |
26 | LAU W, SATTELY E S. Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone [J]. Science, 2015, 349(6253):1224-1228. |
27 | WANG X J, ZHANG X, YANG J T, et al.. Genetic variation assessment of stacked-trait transgenic maize via conventional breeding [J/OL]. BMC Plant Biol., 2019, 19(1):346 [2022-11-13]. . |
28 | WANG X J, ZHANG X, YANG J T, et al.. Effect on transcriptome and metabolome of stacked transgenic maize containing insecticidal cry and glyphosate tolerance epsps genes [J]. Plant J., 2018, 93(6):1007-1016. |
29 | LIU Q S, YANG X W, TZIN V, et al.. Plant breeding involving genetic engineering does not result in unacceptable unintended effects in rice relative to conventional crossbreeding [J]. Plant J., 2020, 103(6): 2236-2249. |
30 | LIU W X, ZHAO H, MIAO C H, et al.. Integrated proteomics and metabolomics analysis of transgenic and gene-stacked maize line seeds [J]. GM Crops Food, 2021, 12(1):361-375. |
31 | LI K, LUO Y B, HUANG K L, et al.. Single universal primer recombinase polymerase amplification-based lateral flow biosensor (SUP-RPA-LFB) for multiplex detection of genetically modified maize [J]. Anal. Chim. Acta, 2020, 1127: 217-224. |
32 | LIU F, LI K, ZHANG Y, et al.. An electrochemical DNA biosensor based on nitrogen-doped graphene nanosheets decorated with gold nanoparticles for genetically modified maize detection [J/OL]. Mikrochim. Acta, 2020, 187(10): 574 [2022-11-13]. . |
33 | 梁晋刚,张开心,张旭冬,等.中国农业转基因生物环境安全检测标准体系现状与展望[J].中国油料作物学报, 2021, 43(1):1-14. |
LIANG J G, ZHANG K X, ZHANG X D, et al.. Current status and prospects of environmental safety standard system for agricultural genetically modified organisms in China [J]. Chin. J. Oil Crop Sci., 2021,43(1):1-14. | |
34 | 张晓磊,章秋艳,熊炜,等.转基因植物检测方法及标准化概述[J].中国农业大学学报, 2020, 25(9):1-12. |
ZHANG X L, ZHANG Q Y, XIONG W, et al.. Overview of detection methods and standardization for transgenic plants [J]. J. Chin. Agric. Univ., 2020,25(9):1-12. | |
35 | WEI S B, LI X, LU Z F, et al.. A transcriptional regulator that boosts grain yields and shortens the growth duration of rice [J/OL]. Science., 2022, 377(6604): 8455 [2022-11-13]. . |
36 | SONG T Z, SHI Y Y, SHEN L K, et al.. An endoplasmic reticulum-localized cytochrome b5 regulates high-affinity K+ transport in response to salt stress in rice [J/OL]. Proc. Nat. Acad. Sci. USA, 2021, 118(50):e2114347118 [2022-11-13]. . |
37 | WU X, FENG H, WU D, et al.. Using high-throughput multiple optical phenotyping to decipher the genetic architecture of maize drought tolerance [J/OL]. Genome. Biol., 2021, 22(1):185 [2022-11-13]. . |
38 | JIANG S S, LI J, WANG Q Y, et al.. Maize growth promotion by inoculation with an engineered ammonium-excreting strain of nitrogen-fixing Pseudomonasstutzeri [J/OL]. Microorganisms, 2022, 10(10):1986 [2022-11-13]. . |
39 | WU K, WANG S S, SONG W Z, et al.. Enhanced sustainable green revolution yield via nitrogen-responsive chromatin modulation in rice [J/OL]. Science, 2020, 367(6478): 2046 [2022-11-13]. . |
40 | YANG J Q, XIE X Q, XIANG N, et al.. Polyprotein strategy for stoichiometric assembly of nitrogen fixation components for synthetic biology [J]. Proc. Natl. Acad. Sci. USA, 2018, 115(36):8509-8517. |
41 | YANG J G, XIE X Q, WANG X, et al.. Reconstruction and minimal gene requirements for the alternative iron-only nitrogenase in escherichia coli [J]. Proc. Natl. Acad. Sci. USA, 2014, 111(35):3718-3725. |
42 | WANG C, WANG X J, ZHANG L W, et al.. Intrinsic and extrinsic programming of product chain length and release mode in fungal collaborating iterative polyketide synthases [J]. J. Am. Chem. Soc., 2020, 142(40):17093-17104. |
43 | WANG X J, WANG C, DUAN L X, et al.. Rational reprogramming of O-methylation regioselectivity for combinatorial biosynthetic tailoring of benzenediol lactone scaffolds [J]. J. Am. Chem. Soc., 2019, 141(10):4355-4364. |
44 | CAI T, SUN H, QIAO J, et al.. Cell-free chemoenzymatic starch synthesis from carbon dioxide [J]. Science, 2021, 373(6562):1523-1527. |
45 | ZHU Q, ZENG D, YU S, et al.. From golden rice to aSTARice: bioengineering astaxanthin biosynthesis in rice endosperm [J]. Mol. Plant., 2018, 11(12):1440-1448. |
46 | ZHANG T, YAN Y Y, HE S, et al.. Involvement of the ammonium transporter AmtB in nitrogenase regulation and ammonium excretion in pseudomonas stutzeri A1501 [J]. Res. Microbiol., 2012, 163(5):332-339. |
47 | 燕永亮,田长富,杨建国,等.人工高效生物固氮体系创建及其农业应用[J].生命科学,2021,33(12):1532-1543. |
YAN Y L, TIAN C F, YANG J G, et al.. Establishment of artificial efficiency biological nitrogen fixation system and its agricultural application [J]. China Bull. Life Sci., 2021,33(12):1532-1543. | |
48 | 燕永亮,王忆平,林敏.生物固氮体系人工设计的研究进展[J].生物产业技术,2019 (1):34-40. |
YAN Y L, WANG Y P, LIN M. Advancement in artificial design of biological nitrogen fixation system [J]. Biotech. Business., 2019 (1):34-40. | |
49 | 马德英,于长磊,艾鹏飞.转C4基因水稻的研究现状及展望[J].分子植物育种,2017,15(10):3997-4002. |
MA D Y, YU C L, AI P F. Progress and perspectives of transgenic rice overexpressing C4 photosynthetic genes [J]. Mol. Plant. Breed., 2017, 15(10): 3997-4002. | |
50 | 雷瑞鹏,邱仁宗.合成生物学的伦理和治理问题[J].医学与哲学,2019,40(19):38-43. |
LEI R P, QIU R Z. Ethical and governance issues in synthetic biology [J]. Med. Philosophy., 2019,40(19):38-43. | |
51 | 刘旭霞,秦宇. 欧美合成生物学应用的风险治理经验及启示[J].华中农业大学学报(社会科学版),2022 (2):177-184. |
LIU X X, QIN Y. Risk governance experience and enlightenment of synthetic biology application in Europe and the US [J]. J. Huazhong. Agric. Univ (Soc. Sci.), 2022 (2):177-184. | |
52 | 焦悦,付伟,翟勇. RNAi技术在作物中的应用及安全评价研究[J].作物杂志, 2018 (1):9-15. |
JIAO Y, FU W, ZHAI Y. Application of RNAi in crop breeding and its safety assessment [J]. Crops, 2018 (1):9-15. | |
53 | EPSTEIN M M, VERMEIRE T. Scientific opinion on risk assessment of synthetic biology [J]. Trends. Biotechnol., 2016, 34(8):601-603. |
54 | 马延和,江会锋,娄春波,等.合成生物与生物安全[J].中国科学院院刊,2016,31(4):432-438. |
MA Y H, JIANG H F, LOU C B, et al.. Synthetic life and biosecurity [J]. Bull. China Acad. Sci., 2016,31(4):432-438. | |
55 | MALARKEY T. Human health concerns with GM crops [J]. Mutat. Res., 2003, 544(2):217-221. |
56 | GOMEZ-TATAY L, HERNANDEZ-ANDREU J M. Biosafety and biosecurity in synthetic biology: a review [J]. Critical Rev. Environ. Sci. Technol., 2019, 49(17):1587-1621. |
57 | 马丽丽,欧亚昆,任怡佳,等.合成生物学的生物安全风险及其管理对策研究[J].科学与社会, 2022, 12(3):15-32. |
MA L L, OU Y K, REN Y J, et al.. Research on biosafety and management countermeasures of synthetic biology [J]. Sci. Soc., 2022,12(3):15-32. | |
58 | 祁潇哲,贺晓云,黄昆仑.转基因生物食用安全评价技术体系及其发展趋势[J].中国农业大学学报,2019,24(7):71-78. |
QI X Z, HE X Y, HUANG K L. Food safety assessment technology system of genetically modified organisms and its development trend [J]. J. Chin. Agric. Univ., 2019,24(7):71-78. | |
59 | OYE K A, ESVELT K, APPLETON E, et al.. Biotechnology begulating gene drives [J]. Science, 2014, 345(6197):626-628. |
60 | 张维,杨敬宇,化得良.合成生物学治理的国外经验综述及启示[J].医学与哲学,2020,41(3):54-58. |
ZHANG W, YANG J Y, HUA D L. Review and implication of synthetic biology governance in foreign countries [J]. Med. Philosophy., 2020,41(3):54-58. | |
61 | 关正君,裴蕾,魏伟,等. 合成生物学概念解析、风险评价与管理[J].农业生物技术学报, 2016, 24(7): 937-945. |
GUAN Z J, PEI L, WEI W, et al.. Concept analysis, risk assessment and regulation of synthetic biology [J]. J. Agric. Biotech., 2016, 24(7): 937-945. | |
62 | 王盼娣,熊小娟,付萍,等.《生物安全法》实施背景下对合成生物学的监管[J].华中农业大学学报, 2021, 40(6):231-245. |
WANG P D, XIONG X J, FU P, et al.. Regulation of synthetic biology under background of implementing biosafety low [J]. J. Huazhong. Agric. Univ., 2021, 40(6):231-245. | |
63 | EFSA Scientific Committee, MORE S, BAMPIDIS V, et al.. Evaluation of existing guidelines for their adequacy for the food and feed risk assessment of microorganisms obtained through synthetic biology [J/OL]. EFSA J., 2022, 20(8): e07479 [2022-11-13]. . |
64 | EFSA Panel on Genetically Modified Organisms GMO), MULLINS E, BRESSON J L, et al.. Evaluation of existing guidelines for their adequacy for the molecular characterisation and environmental risk assessment of genetically modified plants obtained through synthetic biology [J/OL]. EFSA J., 2021, 19(2): e06301 [2022-11-13]. . |
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