Abstract:

The use of Cry toxins from Bacillus thuringiensis(Bt) to control insect pests is a revolutionary progress in crop production.Change in binding ability between Bt insecticidal proteins and its receptors may be the main mechanism of Lepidoptera insect resistance to Bt toxin.Aminopeptidase N(APN) is one kind of receptors for Bacillus thuringiensis(Bt) toxin in insect midguts.Through discussing its binding capability with Bt toxin,this paper summarizes the molecular biology mechanism of APN gene and Bt resistan..

Key words: Bacillus thuringiensis（Bt）, aminopeptidase N（APN）, receptor, mutation, resistance;

摘要：

使用Bt Cry毒素防治农业害虫是作物生产上的一个革命性的进步,受体与Bt杀虫蛋白结合能力的改变可能是昆虫对Bt产生抗性的主要原因。氨肽酶N(aminopeptidase N,APN)是一类存在于昆虫中肠内的Bt毒素受体蛋白,通过讨论APN与Bt毒素的结合作用,综述了APN基因变异与鳞翅目昆虫Bt抗性相关的分子机理,并介绍了(Bt)Cry毒素与APN相关的作用方式新模型。

关键词: 苏云金芽孢杆菌（Bt） 氨肽酶N（APN） 受体 突变 抗性