关键词: 农药, 固体纳米分散体, 制备方法

Abstract: Pesticide solid nanodispersion is a novel formulation proposed by the combination of nanotechnology and preparation technology of solid dispersion, which is a solidified nanoformulation with pesticide compound in the form of particles and microcrystallines dispersed in a solid hydrophilic matrix. This formulation can avoid the use of any organic solvent and substantially reduce the surfactant content, overcome poor stability bottleneck of the water-based nanoformulations. In addition, the formulation can improve the dispersibility, adhesion and permeability of poorly water-soluble pesticide, and further enhance the bioavailability so to reduce pesticides dosage and residual contamination. This article summarized the preparation methods of solid nanodispersions and their applications in the field of pesticide and medicine. Based on the low efficacy and high residue of pesticide, application of the solid nanodispersion as a new type of pesticide formulation is crucial and has important realistic significance.

Key words: pesticide, solid nanodispersion, preparation method