Abstract: Recently, aquaculture industry in China has developed rapidly and brought huge economic benefits. At the same time, long-term misuse of antibiotics and chemical medicine has led to many problems in environment, drug resistance and food security. It is an eargent need to seak a new technology or new product, which can effectively control aquatic animal diseases, and also be environmental friendly, to partly or completely replace antibiotics and chemical medicine. Phage, as a safe, high effective, non-toxic, and eco-friendly green product, is gradually applied in controlling aquatic animal diseases. This paper introduced the latest research progress on applying phage, its biology and therapy in aquaculture industry, and prospected its future development, so as to provide theoretical and technical support for phage therapy in aquaculture.

Key words: phage, aquaculture, bacterial infection

摘要： 近年来，我国水产养殖业发展迅猛，带来巨大收益的同时，抗生素和化学药物的长期滥用也产生了污染环境、耐药性差和威胁食品安全等诸多问题。亟待寻求一种既能有效控制海水养殖动物疾病、又环境友好的新技术、新产品，以部分或完全替代抗生素或化学药物。噬菌体是一种安全、高效、无毒无害、生态友好的疾病防治绿色产品，相继在陆生和水产动物疾病防治中应用。介绍了噬菌体生物学、噬菌体治疗及噬菌体在水产养殖业中的应用等最新研究进展，展望了噬菌体防治水产养殖病害的前景，以期为噬菌体治疗水产养殖疾病提供理论和技术支持。

关键词: 噬菌体, 水产养殖业, 细菌感染